
The three phases when chromosomes are no longer visible are telophase, cytokinesis, and interphase.
This article explains how chromosomes condense, the different stages of cell division when chromosomes become visible, and the three phases of mitosis when they’re not visible.
In Which Three Phases Are Chromosomes No Longer Visible?
Chromosomes are no longer visible during telophase, cytokinesis, and interphase.
Understanding the different phases of cell division and identifying the phases of chromosome visibility is important as it helps to shed light on the mechanisms that control cell growth and development. {1}
The Different Cell Division Phases
Cell division is the process when a parent cell divides into two or more cells. The two cells thus formed are called daughter cells. There are two ways in which cell division occurs — mitosis and meiosis.
Mitosis is the process of creating new somatic cells, while meiosis creates sex cells (also called gametes) — egg cells in females and sperm cells in males.
One of the primary goals of cell division is to enable the propagation of genetic material from the parent cell to the daughter cells. This is done by the replication and transfer of chromosomes, the carriers of genetic material, and occurs over multiple phases.
Interphase: The First Phase of Cell Division
Interphase is the first stage of cell division, where the cell prepares for mitosis by replicating its DNA. During this phase, the chromosomes are not visible because they are in a less-condensed form called chromatin.
Prophase: The Beginning of Chromosome Condensation
In prophase, the chromosomes begin to condense and become visible under a microscope. The chromatin fibers coil and fold, creating compact, detectable chromosomes.
Metaphase: Chromosomes Align at the Equator
In metaphase, the chromosomes align at the equator of the cell. This alignment is critical for ensuring that each daughter cell receives the correct number and type of chromosomes during division.
Anaphase: Chromosomes Separate and Move Toward Opposite Poles
In anaphase, the chromosomes separate into two identical sets and move toward opposite poles of the cell. This process ensures that each daughter cell receives the correct number of chromosomes.
Telophase: Chromosomes Begin to Decondense
In telophase, the chromosomes begin to decondense and become less visible under a microscope. The nuclear envelope reforms around the two sets of chromosomes.
Cytokinesis: The Division of the Cytoplasm
Finally, cytokinesis occurs, dividing the cytoplasm of the cell into two daughter cells, each with its own set of chromosomes. As the chromosomes remain decondensed, they are not visible in this phase as well.
Significance of Chromosomal Condensation

The process of chromosome condensation is complex and involves several proteins that help compact and organize the DNA. This process ensures that the chromosomes are visible and properly aligned during mitosis.
The three phases where chromosomes are visible (prophase, metaphase, and anaphase) are crucial for ensuring accurate chromosome segregation during cell division. Any errors during these stages can lead to chromosomal abnormalities and potentially harmful genetic mutations.
Understanding the different phases of mitosis and the visibility of chromosomes during each stage is critical for understanding how cells divide and replicate. By understanding this process, we can gain insight into genetic disorders, cancer, and other diseases caused by errors in cell division.
Frequently Asked Questions
Sources:
1 – University of Minnesota: “The Cell Cycle.”